Alzheimer's disease

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Researchers Zero In on First, Subtle Phase of Alzheimer's

Study describes early die-off of certain neurons

(Newser) - Alzheimer's disease appears to damage the brain in two phases, and treatment before the latter stage, when "suddenly things get really bad," is key. That's according to Ed Lein, a senior investigator at the Allen Institute for Brain Science, who worked with nearly 100 colleagues to...

Scientists: Brain Has Built-In Waste Removal System

Cleaning process could get rid of cellular trash that can build up, lead to dementia

(Newser) - A unique peek inside the human brain may help explain how it clears away waste like the kind that can build up and lead to Alzheimer's disease. Brain cells use a lot of nutrients, which means they make a lot of waste. Scientists have long thought the brain has...

'Jeopardy' Singer Greg Kihn Dead of Alzheimer's
'80s Hitmaker Is Dead
of Alzheimer's at 75
OBITUARY
Aug 16, 2024 9:52 AM CDT

'80s Hitmaker Is Dead of Alzheimer's at 75

'Breakup Song' singer Greg Kihn loved Weird Al's cover of 'Jeopardy'

(Newser) - Gen X has lost another of its '80s rockers. The AP reports that Greg Kihn, frontman for the Greg Kihn Band behind "The Breakup Song" and MTV staple "Jeopardy," has died at the age of 75. In a statement, Kihn's management team says he died...

Weight Loss Drug Might Also Help Your Brain

Daily liraglutide injections linked to slower cognitive decline in Alzheimer's patients

(Newser) - A drug similar to Ozempic, used to treat diabetes and obesity, might also be used to treat and slow the progression of Alzheimer's disease, according to a small study. Researchers from Imperial College London observed 204 Alzheimer's patients in the UK over a year. Half were given daily...

'I Think We're Onto Something Important' for Alzheimer's

Scientists believe the protein reelin may help shield brain from aging diseases

(Newser) - "I think we're onto something important for Alzheimer's," MIT neuroscientist Li-Huei Tsai tells NPR , after her team's latest research backs up a pair of previous studies regarding a protein they say may help fend off cognitive decline. That protein, reelin, appears to act as a...

Her Dad Was Losing Memory, So They Took Literal Trip Down Memory Lane

Francesca Mari reflects on how reminiscence therapy factored in during a big trip with her father

(Newser) - When Francesca Mari decided to take a European trip with her aging dad, it wasn't just fun that she was hoping for. Writing for the New York Times , Mari expands on her father's Alzheimer's and how, as dementia started to steal his memories, she hit upon an...

On Alzheimer's, an Advance 'We've All Been Waiting For'

Eli Lilly's donanemab, sold as Kisunla, gets the FDA green light to help slow disease progression

(Newser) - Last summer, the Food and Drug Administration gave the thumbs-up to Leqembi, the first drug shown to slow the progression of Alzheimer's disease. Now, almost a year to the day after that move, the government agency has greenlit a second drug: Eli Lilly's donanemab, sold under the brand...

Gena Rowlands Has Same Disease as Her Character in The Notebook

Son who directed her in 2004 movie says she is 'in full dementia'

(Newser) - Heartbreaking news from filmmaker Nick Cassavetes: He says his mother, Gena Rowlands, has Alzheimer's disease, like her character Allie did in The Notebook, which he directed. In the 2004 movie, Rowlands, now 94, played the older version of the character played by Rachael McAdams. "I got my mom...

On the Alzheimer's Front, 'New Avenues' Have Opened

Research suggests rare gene mutation helps delay onset of disease's symptoms in some individuals

(Newser) - Researchers have hit upon a genetic quirk that seems to delay onset of the symptoms of Alzheimer's disease—sometimes for years, or even decades. "It opens new avenues," says neuropsychologist Yakeel Quiroz of Massachusetts General Hospital, a lead author of the new study published Wednesday in the...

Expert Panel Recommends FDA Approve Alzheimer's Drug

Advisers vote unanimously to back donanemab despite risks

(Newser) - A closely watched Alzheimer's drug from Eli Lilly won the backing of federal health advisers on Monday, setting the stage for the treatment's expected approval for people with mild dementia caused by the brain-robbing disease. Food and Drug Administration advisers voted unanimously that the drug's ability to...

Unusual Alzheimer's Predictor: A Falling Credit Score

Study suggests people start making bad financial decisions long before diagnosis

(Newser) - Warning signs of impending Alzheimer's usually focus on the physical—memory slips and the like. A new study out of Georgetown, however, suggests that a declining credit score might also be a sign of trouble:
  • People were 17% more likely to fall behind on their mortgage payments a year
...

Research May Result in Big Spike of Alzheimer's Diagnoses

Two copies of a certain gene would lead to a diagnosis, not merely a warning of risk

(Newser) - A new study has the potential to lead to a dramatic spike in the number of diagnosed Alzheimer's cases in the US—as in, hundreds of thousands of people who aren't even experiencing symptoms. The research published in Nature Medicine suggests that people who have two copies of...

Jay Leno Is Complimented as He's Made Conservator of Wife

Mavis Leno, 77, who has dementia, sometimes doesn't know husband, per report by attorney

(Newser) - Jay Leno was granted conservatorship of his wife of more than four decades on Tuesday in a court hearing that was filled with praise for the care he has given her. Mavis Leno, 77, is suffering from advanced dementia, and People reports that Mavis' lawyer expressed her "agreement" with...

The Globe's Leading Ailments Are in Our Heads
The Globe's Leading
Illnesses Are in Our Heads
NEW STUDY
Mar 18, 2024 9:13 AM CDT

The Globe's Leading Illnesses Are in Our Heads

Neurological conditions like stroke, dementia affect 43% of global population, per new research

(Newser) - The leading cause of all ill health and disability around the globe isn't cancer or heart disease—it's a wide umbrella of neurological conditions, ranging from migraines to strokes, dementia, or Parkinson's, among other maladies. Per a new study published Thursday in the Lancet , scientists found that...

'Subtle' Signs May Point to Dementia Precursor

More attention is being paid to ailment known as Mild Cognitive Impairment

(Newser) - We all experience forgetfulness, but a growing number of doctors are focusing on when harmlessness crosses into a condition known as mild cognitive impairment (MCI). Both the New York Times and the Washington Post have stories on the ailment, which is thought to be severely underdiagnosed—a problem because early...

FDA Delays Approval of Eli Lilly's Alzheimer's Drug
FDA Stalls on New
Alzheimer's Drug
Mar 8, 2024 8:55 AM CST

FDA Stalls on New Alzheimer's Drug

'We were not expecting this,' says Eli Lilly president

(Newser) - Eli Lilly's experimental Alzheimer's drug is facing yet another delay on the path toward FDA approval. The company's donanemab medication was first expected to be cleared last year and later by the end of this month. However, the drugmaker announced Friday that approval isn't expected until...

Viagra Study Provides 'Food for Thought'
Viagra Study
Provides 'Food
for Thought'
in case you missed it
Feb 18, 2024 7:00 AM CST

Viagra Study Provides 'Food for Thought'

Researchers find correlation between Viagra prescriptions, lowered Alzheimer's risk

(Newser) - It's an intriguing study that provides "food for thought," as its lead author puts it. Researchers found men who'd been prescribed Viagra and similar PDE5 inhibitor drugs were 18% less likely to develop Alzheimer's over a five-year period than those who hadn't been prescribed...

Researchers Find Telltale Alzheimer's Clues in Our Blood

Study identifies 4 biological markers, raising hope that a blood test for dementia is nearer

(Newser) - It's looking more and more likely that a blood test to predict Alzheimer's years before symptoms appear will be available in the not-too-distant future. In the latest development, researchers say they identified biological markers in stored blood samples that reliably forecast various forms of dementia nearly 15 years...

Ancient Greeks Didn't Seem to Get Dementia


Ancient Greeks
Didn't Seem
to Get
Dementia
NEW STUDY
Feb 11, 2024 12:40 PM CST

Ancient Greeks Didn't Seem to Get Dementia

Findings bolster theories that cognitive decline is linked to modern lifestyle, environment

(Newser) - A new study that went deep into ancient Greek and Roman medical texts suggests that dementia was rare 2,000 to 2,500 years ago. HealthDay notes the analysis builds on the theory that modern cognitive decline is linked to lifestyle and environmental factors. The findings, published in Journal of ...

For These 5, Alzheimer's Was Medically Acquired
Medical Miscue May Have
Given Patients Alzheimer's
NEW STUDY
Jan 30, 2024 11:49 AM CST

Medical Miscue May Have Given Patients Alzheimer's

Study suggests disease was triggered by human growth hormone shots derived from cadavers

(Newser) - Doctors once sought to make very short children taller by injecting them with growth hormone taken from the brains of dead people. The procedure was banned 40 years ago—and cadaver-derived pituitary growth hormone (c-hGH) replaced with a synthetic version—when scientists discovered patients had also received bits of protein...

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